Extracellular vesicles (EVs) are small, membrane-bound particles that are secreted by all cell types. They vary in size, typically ranging from 20 to 5000 nm, and carry a diverse array of biomolecules, including proteins, lipids, and nucleic acids. Hence, EVs play a key role in cell-to-cell communication by transferring their cargo to target cells.
SMLM can give insights on the size, composition and morphology of single vesicles and the entire population, in one quick, simple high-throughput measurement.